In this paper we report on the first scintigraphic evaluation of vaginal dosage forms in post-menopausal women. To date, almost nothing is known about the in vivo performance of pharmaceutical formulations in the human vagina, which is a major deficiency in the rational design of drug delivery systems for both existing and new indications. In five out of the six subjects studied, clearance of the two formulations exhibited very little intra-subject variation. Importantly, there was no evidence to suggest that either of the formulations dispersed material beyond the cervix, into the uterus, in any of the subjects studied.
Preparing for a Gentle Birth: How to Stretch Your Vagina
If vaginal cancer spreads - Canadian Cancer Society
A pre-cancer is a condition where some cells look abnormal. These cell changes are not cancer, but could become cancer over time. Vaginal intraepithelial neoplasia or VAIN means that the changed cells are only found in the innermost surface layer of the vagina. VAIN is more common in women who have had their uterus removed hysterectomy and in those who were treated for cervical cancer or pre-cancer in the past. VAIN3 is the closest to a true cancer.
Cancer cells can spread from the vagina to other parts of the body. This spread is called metastasis. Understanding how a type of cancer usually grows and spreads helps your healthcare team plan your treatment and future care. If vaginal cancer spreads, it can spread to the following: vaginal wall tissues around the vagina pelvic wall lymph nodes in the pelvis or groin bladder urethra rectum lungs , bones , liver.
Renowned birthing coach, author, and founder of The Gentle Birth Method, Dr Gowri Motha, shares the amazingly simple and intelligent way of pre-stretching your vagina for the gentle release of your baby. The pelvic floor muscles surrounding the vagina are elastic and can stretch and tighten. Certain events can lead to changes in vaginal tension, and this includes childbirth. Vaginal stretching can also ensure that the vagina and perineum remain intact following childbirth.