New drug treatment for female sexual dysfunction

In certain populations of women that we see in our clinic, including women treated with serotonergic antidepressants and perimenopausal women, rates of sexual dysfunction are even higher. While its precise mechanism of action is not known, it is hypothesized that flibanserin may enhance sexual desire by increasing levels of dopamine and norepinephrine while transiently decreasing serotonin levels. The use of flibanserin has been limited as it is has been FDA-approved only for premenopausal women with acquired HSDD which is HSDD developing in a woman who has previously had no problems with sexual desire. Furthermore, it has a long list of drug-drug interactions , including commonly used antidepressants, such as fluoxetine and sertraline. In addition, it has a black box warning regarding its use with alcohol, a combination that has been associated with hypotension and syncopal episodes.
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Vyleesi? Addyi? How women can get help for low sexual desire

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Female sexual dysfunction - Diagnosis and treatment - Mayo Clinic

Women who feel distressed by a lack of sexual desire may have some help on the way. HSDD is a term coined to describe low sexual desire without a clear cause. The physiology of sexual arousal and desire is complex in women. In research funded by a licensing partner of the drug manufacturer, bremelanotide was studied for both effectiveness and safety.
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Drugs in early clinical development for the treatment of female sexual dysfunction

Your doctor may also refer you to a counselor or therapist specializing in sexual and relationship problems. Keep in mind that sexual dysfunction is a problem only if it bothers you. If it doesn't bother you, there's no need for treatment.
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